Uridine diphosphate

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Uridine diphosphate
Skeletal formula of uridine diphosphate
Ball-and-stick model of the UDP molecule as an anion
Names
IUPAC name
Uridine 5′-(trihydrogen diphosphate)
Systematic IUPAC name
[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl trihydrogen diphosphate
Identifiers
ChEMBL
ChemSpider
ECHA InfoCard100.000.372 Edit this at Wikidata
MeSHUridine+diphosphate
UNII
  • InChI=1S/C9H12N2O6.2H3O4P/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;2*1-5(2,3)4/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);2*(H3,1,2,3,4)/t4-,6-,7-,8-;;/m1../s1 checkY
    Key: PMPFLUWUGZHTOK-WFIJOQBCSA-N checkY
Properties
C9H14N2O12P2
Molar mass404.161
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Uridine diphosphate, abbreviated UDP, is an organic compound. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil.

UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase.[1][2]

See also

[edit]

References

[edit]
  1. ^ Glycogen Biochemistry
  2. ^ "Biochemistry Pathways: Polysaccharide Synthesis". Archived from the original on 2015-04-10. Retrieved 2014-09-20.
Stub icon

This biochemistry article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Uridine_diphosphate&oldid=1282667244"
    Uridine diphosphate
    Skeletal formula of uridine diphosphate
    Ball-and-stick model of the UDP molecule as an anion
    Names
    IUPAC name
    Uridine 5′-(trihydrogen diphosphate)
    Systematic IUPAC name
    [(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl trihydrogen diphosphate
    Identifiers
    • 58-98-0 checkY
    ChEMBL
    • ChEMBL130266 ☒N
    ChemSpider
    • 19952429 checkY
    ECHA InfoCard100.000.372
    • 1749
    MeSHUridine+diphosphate
    • 1158
    UNII
    • 5G0F599A1Y checkY
    • DTXSID001018933
    • InChI=1S/C9H12N2O6.2H3O4P/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;2*1-5(2,3)4/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);2*(H3,1,2,3,4)/t4-,6-,7-,8-;;/m1../s1 checkY
      Key: PMPFLUWUGZHTOK-WFIJOQBCSA-N checkY
    Properties
    C9H14N2O12P2
    Molar mass404.161
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
    ☒N verify (what is checkY☒N ?)

    Uridine diphosphate, abbreviated UDP, is an organic compound. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil.

    UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase.[1][2]

    See also

    References

    1. ^ Glycogen Biochemistry
    2. ^ "Biochemistry Pathways: Polysaccharide Synthesis". Archived from the original on 2015-04-10. Retrieved 2014-09-20.
    Stub icon

    This biochemistry article is a stub. You can help Wikipedia by expanding it.

    Retrieved from "https://en.wikipedia.org/w/index.php?title=Uridine_diphosphate&oldid=1282667244"